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Pelitinib
Synonyms: EKB569
CAS NO: 257933-82-7
Molecular Formula: C24H23ClFN5O2
Molecular Weight: 467.92
Purity: 99%
Package: 1g/bag 5g/bag ,labs product.
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Remarks: Pelitinib is a 3-cyanoquinoline pan-ErbB tyrosine kinase inhibitor with potential antineoplastic activity. Pelitinib irreversibly binds covalently to epidermal growth factor receptors (EGFR) ErbB-1, -2 and -4, thereby inhibiting receptor phosphorylation and signal transduction and resulting in apoptosis and suppression of proliferation in tumor cells that overexpress these receptors. Pelitinib inhibits EGF-induced phosphorylation of EGF-R and the growth of tumors that overexpress EGF-R in animal models.

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