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Home Products Asenapine Maleate
Asenapine Maleate
Synonyms: Saphris
CAS NO: 85650-56-2
Molecular Formula: C17H16ClNO.C4H4O4
Molecular Weight: 401.84
Purity: 99%
Package: 1g/bag 5g/bag ,labs product.
Storage: −20°C 2 years
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Remarks: Asenapine (Saphris) is a new atypical antipsychotic developed for the treatment of schizophrenia and acute mania associated with bipolar disorder. Asenapine shows high affinity (pKi) for numerous receptors, including the serotonin 5-HT1A (8.6), 5-HT1B (8.4), 5-HT2A (10.2), 5-HT2B (9.8), 5-HT2C (10.5), 5-HT5A (8.8), 5-HT6 (9.5), and 5-HT7 (9.9) receptors, the adrenergic ¦Á1 (8.9), ¦Á2A (8.9), ¦Á2B (9.5), and ¦Á2C (8.9) receptors, the dopamine D1 (8.9), D2 (8.9), D3 (9.4), and D4 (9.0) receptors, and the histamine H1 (9.0) and H2 (8.2) receptors. Asenapine behaves as an antagonist at all receptors.

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