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Home Products Motesanib diphosphate Motesanib diphosphate Synonyms: CAS NO: 857876-30-3 Molecular Formula: 569.45 Molecular Weight: 569.45 Purity: 98% min Package: 1G/BAG 5G/BAG,LAB PRODUCTS Storage: -20�� Order Order Infomation Remarks: Motesanib (AMG-706) is an orally bioavailable diphosphate salt of a multiple receptor tyrosine kinase inhibitor with potential antineoplastic activity[1]. This reagent selectively targets and inhibits VEGFR1/2/3(IC50: 2 nM /3 nM /6 nM), PDGFR (84nM), kit (8nM), and Ret (59nM)receptors, thereby inhibiting angiogenesis and cellular proliferation. Oral administration of AMG 706 potently inhibited VEGF-induced angiogenesis in the rat corneal model and induced regression of established A431 xenografts Quality Control Quality Control by H-NMR,C-NMR,LC-MS,HPLC. Related Products Tinib Series Axitinib Amuvatinib MP-470 BIBW2992 Bafetinib Brivanib Bosutinib Cediranib Canertinib Cabozantinib Crizotinib dovitinib lactate Dasatinib Erlotinib hydrochloride E7080 lenvatinib Foretinib Fostamatinib disodium Gefitinib INCB 018424 Ruxolitinib Lapatinib Linifanib abt869 Linsitinib OSI-906 Lonafarnib Lapatinib ditosylate Motesanib Motesanib diphosphate Masitinib Mubritinib Neratinib Nilotinib Olaparib PLX-4032 Pelitinib Pazopanib hydrochloride Pazopanib Ponatinib Quizartinib AC-220 Regorafenib Sunitinib malate Sorafenib tosylate Saracatinib Tipifarnib (Zarnestra) Tandutinib Tivozanib Volasertib Vandetanib   None of the products will be supplied to countries in which this could be in conflict with the existing patents. However the final responsibility lies with the Buyer.

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