Home Products SRT1720
SRT1720
Synonyms:
CAS NO: 1001645-58-4
Molecular Formula: C25H23N7OS.HCl
Molecular Weight: 506.02
Purity: 98% min
Solubility: In DMSO
Storage: -20°C
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Remarks: SRT1720 is a selective activator of human SIRT1 (EC1.5 = 0.16 M and maximum activation = 781%) versus the closest sirtuin homologues, SIRT2 and SIRT3(SIRT2: EC1.5 = 37 MSIRT3: EC1.5 > 300 M). This agent binds to the SIRT1 enzyme-peptide substrate complex at an allosteric site amino-terminal to the catalytic domain and lower the Michaelis constant for acetylated substrates.

Quality Control

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