Home Products CUDC 907;CUDC907
CUDC 907;CUDC907
Synonyms:
CAS NO: 1339928-25-4
Molecular Formula: C23H24N8O4S
Molecular Weight: 508.55
Purity: 98% min
Solubility: In DMSO
Storage: -20 oC
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Remarks: CUDC-907 is an orally bioavailable inhibitor of both phosphoinositide 3-kinase (PI3K) class I and pan histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon oral administration, CUDC-907 inhibits the activity of both PI3K class I isoforms and HDAC, thereby preventing the activation of the PI3K-AKT-mTOR signal transduction pathway that is often overactivated in many cancer cell types. This may prevent growth of PI3K and/or HDAC-expressing tumor cells. CUDC-907 shows an increased inhibition of tumor cell growth and induction of apoptosis when compared to inhibitors that target either PI3K or HDAC. Check for active clinical trials or closed clinical trials using this agent.

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