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Home Products LY335979 LY335979 Synonyms: Zosuquidar CAS NO: 167465-36-3 Molecular Formula: C32H31F2N3O2.3HCl Molecular Weight: 636.99 Purity: 98% min Package: 1g/bag 5g/bag...labs products Storage: -20°C Order Order Infomation Remarks: LY335979(Zosuquidar) is a selective Pgp (P-glycoprotein) inhibitor with a Ki of 59 nM, and does not modulate MRP-mediated resistance by MRP1 (ABCC1) and MRP2 (ABCC2). LY335979 significantly enhanced the survival of mice implanted with Pgp-expressing murine leukemia (P388/ADR) when administered in combination with either daunorubicin, doxorubicin or etoposide. Coadministration of LY335979 with paclitaxel compared to paclitaxel alone significantly reduced the tumor mass of the Pgp-expressing UCLA-P3.003VLB lung carcinoma in a xenograph model. LY335979 was without significant effect on the pharmacokinetics of these anticancer agents. Quality Control Quality Control by H-NMR,C-NMR,LC-MS,HPLC. Related Products Others (S)-tert-butyl 3-oxo-1-phenylpropylcarbamate (R,R)-(-)-1,2-BIS[(O-METHOXYPHENYL)(PHENYL)PHOSPHINO]ETHANE(1,5-CYCLOOCTADIENE)RHODIUM (I) TETRAFLUOROBORATE (2R,3S)-3-(tert-Butoxycarbonyl)amino-1,2-epoxy-4-phenylbutane (1R,3s,5S)-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo[3.2.1]octane (2S)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile (R)-Lansoprazole (S)-2-(1,6,7,8-Tetrahydro-2H-indeno[5,4-b]furan-8-yl)ethylamine 1095382-05-0 1-Piperidinepropanol,a,a-diphenyl-,1-methanesulfonate 1-(4,5-Diamino-10-aza-tricyclo[6.3.1.0]dodeca-2,4,6-trien-10-yl)-2,2,2-trifluoro-ethanone 3-BROMO-5-(2-PYRROLIDINYL)PYRIDINE 4SC-201(resminostat,BYK408740) 4-Amino-2-bromopyridine 518-34-3 7-Dehydrocholesterol A 769662 Almotriptan ABT-263 AZD8055 AZD 1480 AR-42 ADL-5859 Andarine AZ 3146 Argatroban AG 490 Azatadinemaleate Agomelatine AS-252424 AS-605240 Alovudine AZ 960 AS-604850 Abiraterone Acetate AZ 23 ARRY-543 ARRY380 alpha,alpha-Diphenyl-4-piperidinomethanol AZD8931 abiraterone Anacetrapib A66 Atomoxetine hydrochloride Ambrisentan AT13387 Allopurinol AZD7762 Aprepitant Blonanserin BIX 02188 BMS-946815 BIX 02189 BMS777607 Belinostat (PXD101) Bosentan hydrate Brinzolamide BMS 794833 BAN ORL 24 BMS-599626 BMS-903710 BMS-790052 BI 2536 BIBR-953 BIBF-1120 Benzbromarone CUDC-101 Canagliflozin CHIR99021 Cilomilast CCT128930 CYC116 Cefoxitin sodium CP 690550 Cidofovir hydrate Cidofovir Cyclopamine Calcitriol CX-4945 CAL-101 Ciprofibrate Cyt387 cetilistat Clemastine Fumarate CK1827452 cis-Jasmone Cerivastatin Cerivastatin sodium CH 5424802 CX-5461 CAY10505 Clopidogrel bisulfate Ceftibuten dihydrate Chlorine e6 Crenolanib CHIR-265 or RAF265 DCC-2036 DMXAA DAPT Doripenem hydrate Dabigatran etexilate Dorzolomide hydrochloride Darifenacin hydrobromide Dapagliflozin Dapoxetine hydrochloride Danoprevir Doramapimod Dalcetrapib/JTT705 Enzastaurin Eflornithine HCl Ethyliminum EX 527 Fondaparinux sodium Fenticonazole nitrate FG-4592 GW788388 Gabapentin hydrochloride GDC-0449 Vismodegib Ganetespib GSK 1120212 Gemfibrozil GSK 2126458 GSK1349572 GW 501516 Gestodene GSK 690693 GSK256066 GDC-0879 GDC0941 GDC-0980 GSK1904529A GW 843682X H-89 dihydrochloride HMN-214 ICG-001 IC-87114 Ivabradine hydrochloride INNO-206 JNJ7706621 JNJ 38877605 KU-55933 Ki16425 ku0063794 KU-60019 KN-62 LY2603618,IC-83 LY2157299 LDN193189 Lacosamide Laninamivir LY335979 LY315920(Varespladib) Liranaftate Lornoxicam LY2811376 LY2228820 MK-2206 MDV3100 MGCD-265 Melanotan II Moxidectin MRS 2578 MK-0524 Milbemycin oxime MG-132 MK-8245 MGCD0103 (Mocetinostat) Minodronic acid MK-0752 MCOPPB trihydrochloride MRE-269 Mildronate MK-1775 Merck-5 NVP-BGJ398 NVP-AEW 541 NVP-BHG712 NVP-BGT226 Nitrocaphanum NVP-LDE225 NVP-TAE684 NVP-BEZ 235 NU7441 NVP-BKM-120 OSI-027 Olopatadine Ozagrel Ostarine osi-420 Org 27569 OSU-03012 PD 0325901 Pimecrolimus Prucalopride PD 184352 Prucalopride Succinate PLX 4720 PP242 PIK-90 PD98059 PF-04971729 PI-103 PNU120596 PF-04217903 PH 797804 PF03716556 Panobinostat PF-00562271 PKI-587 PF3845 PD0332991 PX-478 dihydrochloride PF299804 PF-04929113 PCI-32765 PF-562271 Perifosine PF-00299804 dacomitinib PD173074 RO4929097 Rilpivirine RU-58841 Rebamipide R406 Roscovitine Ramelteon Rotigotine hydrochloride S31-201 (NSC 74859) SB 271046 hydrochloride SRT1720 Solifenacin succinate SRT3109 Sofalcone SCH727965 SNS-032 Sodium ceftiofur SB 203580,RWJ 64809,PB 203580 SNX-2112 SB939 SB-737050-A SU11272 SU5402 SU11274 Silodosin SB590885 Sitaxsentan sodium Selumetinib Telaprevir TG100-115 TOK-001 Tivantinib ARQ-197 Ticagrelor Torin 2 Thiazovivin Torasemide Triciribine TSU-68 TAME Tozasertib Tolvaptan TG101209 Topotecan hydrochloride TG 101348 TAK-901 Torin 1 tert-butyl 4-((5R,7S)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazine-1-carboxylate Ubenimex URB597 U0126 UK 383367 Vindoline VX-765 VX 222 Vildagliptin Veliparib VX702 VX-809 WZ4002 WAY-100635 maleate salt WYE 125132 WP1130 XL 147 Y27632 Zaltoprofen Zibotentan ZM 241385 [1-(5-Fluoropentyl)-1H-indol-3-yl]-1-naphthalenylmethanone   None of the products will be supplied to countries in which this could be in conflict with the existing patents. 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