Home Products L189
L189
Synonyms:
CAS NO: 64232-83-3
Molecular Formula: C11H10N4OS
Molecular Weight: 246.29
Purity: 98% min
Solubility: In DMSO
Storage: -20°C
Availability and Price
If the item is temporarily out of stock. Please email to order@pharm-intermediates.com,we will inform you when we have it in stock.
Order       Order Infomation
Shipping and handling fee USD40
Free delivery is qualified when the total value of your order exceeds 500USD
Remarks: L189 is a DNA ligase I, III and IV inhibitor (IC50 values are 5, 9 and 5 M respectively) that blocks DNA binding. L189 inhibits base excision repair (BER) and non-homologous end joining (NHEJ). L189 specifically sensitizes cancer cells to DNA damage and increases the cytotoxicity of DNA-damaging agents. L189 will not only provide insights into the cellular function of these enzymes but also serve as lead compounds for the development of anticancer agents.

Quality Control

Quality Control by H-NMR,C-NMR,LC-MS,HPLC.
Related Products
Custom Synthesis
(+)-JQ-1
(R)-P7C3-OMe
1-(3-Methoxybenzyl)-3-[4-(pyridin-4-yl)thiazol-2-yl]urea
2,6-difluoro-3-(propylsulfonamido)benzoic acid
2-chloro-11-cyclopentyl-5H-benzo[e]pyrimido[5,4-b][1,4]diazepin-6(11H)-one
3-Angeloylingenol
3-Quinolinecarboxylic acid, 7-(3,5-dimethyl-4-isoxazolyl)-4-hydroxy-6-methoxy-
4SC-201(resminostat,BYK408740)
4SC-202 free base
5-tert-butoxyquinazoline-2,4-diamine
5,6-trans-1a,25-Dihydroxyvitamin D3
5-[9-Isopropyl-d7-2-(4-morpholinyl)-9H-purin-6-yl]-2-pyrimidinamine
6-Fluoro-3-hydroxypyrazine-2-carboxamide
Amlodipine
Apoptosis Activator 2
APD668
AT13148;AT 13148; AT-13148
ABT-263 (Navitoclax)
ACTB-1003
AMD 3465 hexahydrobromide
ASP 3026
Alfacalcidol
ARN-509
AT 56
AMG-073 HCl (Cinacalcet HCl)
Actinomycin D
Ampalex CX-516
AR-A014418
Apremilast
AdipoRon
AZD1208
AT-406
Ametantrone(NSC 196473)
AZD-4547
AG 18; AG 18 (pharmaceutical); RG 50810; RG 50858; TX 825; Tyrphostin 23; Tyrphostin A 23; Tyrphostin AG 18
AZ 23
ATB 346
AWD 131-13
AT 101
AG1024
Ansamitocin P 3
AT 7867
AZD-3514
AZD-3463
APY 29
ABT-737
A-740003
AMG 517
A-803467
AP23848 PF-562771
AG-490
AM555S,TAC-101,Amsilarotene
Atorvastatin sodium salt
AST-1306
A 796260
Alvelestat (AZD9668)
AZD5363
Angiotensin acetate
Argireline
Atglistatin
ABT-199 (GDC-0199)
Avosentan; Ro 67-0565 SPP-301
AVL-292
Anamorelin
AGI-6780
AN-2690(Tavaborole)
AN 2728
Amrubicin
AGI-5198 (IDH-C35)
Atosiban Acetate
ABT-333
APY0201
A 769662
A 922500
AZD7762
Aprepitant (MK-0869)
Alvespimycin
Ascomycin
AZ5104
ADL-5859 HCL
Abiraterone Acetate
Aliskiren Hemifumarate
ARRY-543
Amiodarone hydrochloride
Bremelanotide PT 141
BMN 673
BML 190
BMN-673; LT-673
BMS 303141
Bioymifi
Baricitinib INCB 028050 LY3009104
BMS-708163 (Avagacestat)
BMS-791325;Beclabuvir
BMS-790052
BMS663068 Fostemsavir
BMH-21
Boceprevir
BI6727 (Volasertib)
Brivudine;Bromovinyldeoxyuridine
Bazedoxifene
BNC105P
BMS-536924
Bafilomycin A1
BI-D1870
Bexarotene
BMS-903710
BI 2536
BMS-946815
BX-912 BX912;BX 912
BX795 BX-795
Birinapant (TL32711)
BMS-345541
BRD73954
BMS-806 (BMS 378806)
BMS-599626
BIBR-953
B-Raf IN 1
BMS833923 XL-139
BMS-754807; BMS754807; BMS 754807
BAN ORL 24
CPI 203
Cilomilast (SB-207499)
Cobicistat
CM 346(Obenoxazine); Afobazole
Clemizole hydrochloride
CL-387785(EKI785; WAY-EKI 785)
CTEP
CI-994 (Tacedinaline)
CP-945598 hydrochloride
CTX 0294885;CTX0294885
CX-4945
Celecoxib
CH 223191
CGK 733
CH 223191
CX-6258
CNV1014802(GSK-1014802)
CP 466722
CHIR-124.
Cinaciguat BAY-58-2667
Cordycepin
Carubicin
Cabazitaxel
Clemizole
Catharanthine sulfate
Calcitriol
Cladribine
cis,cis,cis-1,2,3,4-Tetrakis[(diphenylphosphino)methyl]cyclopentane
Calcitonin salmon
Crizotinib (PF-02341066)
Cabazitaxel N-1
cetuximab
CS 610; GM 6001; Ilomastat;
Chidamide(CS055; HBI-8000)
Cidofovir
CCG1423;CCG-1423
c-FMS inhibitor
CP 640186
CID797718
Carfilzomib (PR-171)
Curcumin
Crenolanib (CP-868569)
CH 5424802
CYC116
CK1827452
CDDO-Methyl ester,TP-155C
Canagliflozin
CHIR-99021 (CT99021)
Cyclopamine
CAY10572;PHA 767491
CID 755673
CPI-613
Cariporide
Decernotinib (VX-509)
Deslorelin Acetate
Dapagliflozin
Didesethylflurazepam dihydrochloride
DGAT-3
Doramectin
Dofetilide
Dimethyloxaloylglycine (DMOG)
DMBX-anabaseine;DMXB-A;GTS 21
DMAB-anabaseine
Dimebolin
Dorsomorphin
Dynasore
Dabrafenib
Dihydro-FK 506
Dovitinib (TKI-258, CHIR-258)
dovitinib lactate
DCC-2036 (Rebastinib)
Dacinostat (NVP-LAQ824, LAQ824)
D-64131
DY131
DAPT (GSI-IX)
Detomidine HCl (Dormosedan)
DMXAA
Dapivirine
Delanzomib CEP-18770
Desmopressin acetate
EPZ004777;EPZ 004777;EPZ-004777
Entospletinib
EPZ015666
ECBC hcl; 1-[(4R,5R)-4,5-Dihydroxy-L-ornithine]echinocandin B hydrochloride (1:1)
endo-IWR 1
ethyl 6-(pyrrolidin-1-yl)nicotinate
ethyl 6-chloronicotinate
ELR510444;ELR 510444
Elvitegravir (GS-9137)
Epoxomicin (BU-4061T)
Eltrombopag
Enzastaurin (LY317615)
empagliflozin
EPZ-5676
ENMD-2076 Tartrate
EMD-1214063
ENIPORIDE
Endoxifen
ENMD-2076
Erteberel
Etofenamate
Epothilone D
Ezatiostat; Ter 199; Terrapin 199
Exenatide acetate
Eluxadoline;JNJ 27018966
Eltrombopag olamine
EPZ6438; EPZ 6438; E-7438
Eravacycline TP-434
Eptifibatide
Fondaparinux sodium
FUB 359 maleate salt
FLLL32
Flupenthixol dihydrochloride
FL118
FG-4592
Fludarabine phosphate
FAI;5S rRNA modificator
FLI-06
Flupenthixol dihydrochloride
FK-3311;FK3311
Fidaxomicin
FK866 (APO866)
Fostamatinib disodium
FUB 359
Fingolimod hydrochloride
Fenretinide (4-HPR)
GSK 650394
GSK525762 (I-BET-762)
GSK-3InhibitorI,TDZD-8;NP 01139
GSKJ1;GSK J1
GSK256066
Geldanamycin
GS-7340(Tenofovir alafenamide)
GW 843682X
GSK 1070916
GW 9662
GW 7647
GW 5074
GSK-503;GSK503
GSK1292263
Glycine isopropyl ester hydrochloride
GNF 5837
GW 441756
GNF-2
GIT 27; VGX 1027
Gonadorelin acetate
GDC 0623
GSK1349572
GW 9508
GW3965 HCl
Growth hormone releasing peptide;GHRP-6
GSK 429286 A
GSK 2578215A
GSK-2606414;GSK2606414
GDC 0068
GSK 1059615;GSK1059615
GW 501516
Gonadorelin acetate
GLPG0634(filgotinib)
GBR 12935 dihydrochloride
GBR 12935 dihydrochloride
gsk 126 gsk126
GANT 61
GSK 2334470;GSK2334470
Golvatinib (E7050)
GW-6604
Genz-123346
GW2580
GSK1904529A
Gambogic acid
GSK 3787
GSK1210151A
GW788388
Hexarelin
H-89 dihydrochloride
HQL 79
HBX 41108
HPGDS inhibitor-1
HA14-1
HA 1100 hydrochloride
HMN-214
IRAK-1-4 Inhibitor I
Indacaterol
Inolitazone
Ibutamoren mesylate MK-677
ICG-001
Idoxifene
IU1
IRAK inhibitor 6
Istaroxime;PST-2744
IOX2
INNO-206
Indisulam
IKK-IN-1
INCB 3284 bimesylate
ICA 121431 ICA-121431
Isoindigotin
Ingenol
ICG-001
ISRIB
ISRIB
Idasanutlin (RG-7388);RG 7388
IOWH032
IWP-2
Ixabepilone
JIB04
JTC 801
JDTic 2HCl
JZL 184
J-147;J147;J 147
JAK2 Inhibitor V Z3
JNJ 26854165 JNJ-26854165 Serdemetan
JW55;JW 55;JW-55
Kobe 2602
KU-55933
KB-R7943 mesylate
Ki-20227
Ki16425
Kanamycin sulfate
Kobe0065
kb-NB77-78
KN-62
KPT-330, (E)-RN
KX1-004
KU 0060648 trihydrochloride
KU-60019
KU14R
Linaclotide
LDC1267
Lesinurad(RDEA594) sodium
LY-2584702;LY2584702
Lithospermic acid B
LY2811376
LB-100
Leuprorelin acetate
LH846
LY2183240
Laquinimod (ABR-215062)
LY364947
LY2874455
Lecirelin (Dalmarelin) Acetate
LHW090-A7
LY315920(Varespladib)
Ledipasvir GS 588
Lonafarnib
LY335979
Linagliptin (BI-1356)
LRRK2-IN-1
LDN193189
LY2603618,IC-83
LY 2109761
Lypressin Acetate
LY2940680
LY2157299
Laninamivir
LCZ696
LY2608204
LY 2886721 hydrochloride salt
LY2886721
L189
Lersivirine(UK 453061)
Linsitinib OSI-906
LY2801653
LGD 4033;LGD-4033
LDK378
Micafungin FR-179642 impurity (acid)
Macitentan
Marbofloxacin
MBX-2982
MDA 19
Malonoben
Mizoribine
MK 4305
MK 3207
MS436
MK-8245
Maxacalcitol
MPEP
Melanotan-1
MDL 29951
MK 0812
ML 161;ML161
ML 323
M344
Melanotan II
MK-0524
MLN120B
Merck-5
Mitozolomide
MK-0752
MK-886
Mdivi-1
Mitomycin C
Miriplatin
MRS 2578
MCOPPB trihydrochloride
Molidustat;BAY85-3934
ML 7 hydrochloride
MEK162 (ARRY-162)
Midostaurin (PKC412)
MK-1775
MK-2048
MRE-269
MK-8245
N-benzyl-N-methyl-1-(4-(trifluoromethyl)benzyl)piperidine-3-carboxamide
NVP-BGJ398
NSC 405020
NITD 609
NVP-LDE225
Necrostatin-1
NS309
NSC-339555;BRYOSTATIN;BRYOSTATIN 1
NVP-TAE684
Nutlin 3
Nepicastat hydrochloride RS 25560-197
NSC697923
Nocodazole
Nutlin-3a
N6022
Naxagolide Hydrochloride
Naxagolide
NSC 405020
Nicaraven
N-benzyl-2-(6-bromo-2-methylquinolin-4-yloxy)acetamide
Nimorazole
Nexturastat A
NLG919
NPS-2143 (SB262470)
N-(4-iodopyridin-3-yl)pivalamide
N-(Pyridin-3-yl)pivalamide
Nedocromil
NVP-AEW 541
NU7441
Naltrexone hydrochloride
Oligomycin A
oritavancin,LY333328 phosphate salt
Oclacitinib maleate
OC000459
Obatoclax Mesylate; GX15-070
Olmesartan medoxomil
Org 27569
OSU-03012
Oclacitinib PF-03394197
Octreotide Acetate
Orlistat
ON 01910 sodium salt;Rigosertib
Odanacatib MK-0822
osi-420
ONX0912
OSI-027
Oxytocin Acetate
OTX015
P505-15
PF03716556
Posaconazole
PNU120596
PYR-41
PF 8380
PF-04971729
PF 477736
PD0332991
PJ 34 hydrochloride
PF 3274167
PPQ-102
Prucalopride Succinate
Purvalanol B(NG 95)
Pentostatin
P7C3
PF 573228
PD 169316
Plerixafor 8HCl (DB06809)
Purvalanol A(R)-Purvalanol A; NG 60
PF 429242
PF 04449913
Pimecrolimus
PTC124 (Ataluren)
Picropodophyllotoxin
PQ401
PX-478 dihydrochloride
Piplartin;Piperlongumine
PF-06687859
Plerixafor
Prucalopride
PF3845YNE
PA-824
PF-431396
PR 957ONX 0914
PF-5274857
Perampanel
PAI 039 Tiplaxtinin
PF-2545920
Palmitoyl Pentapeptide
PFI-2
PU-H 71
Parecoxib
PF 3845
Purmorphamine
P22077
P7C3-A20
P5091 (P005091)
Polymyxin B sulfate
Pyroxamide
PP 121
PR-619
Prasugrel metabolite
Parecoxib sodium
PFI-1(PF-6405761)
PND-1186;PND1186
Pixantrone
PSI 7977 Sofosbuvir
PU-WS13
PluriSln 1
PP2
Pralatrexate
PF-4708671;PF4708671;PF 4708671
PI-3065
PP 1
PF 3758309
Pralmorelin
QS 11
QNZ (EVP4593)
Quizartinib AC-220
RostafuroxinPST2238
Roflumilast
Regadenoson
Ro 3306
Reversine
RoMidepsin Depsipeptide(FK-228,NSC-63017)
Radotinib; IY5511 HCl
Ro 61-8048
Rebeprazole sodium
RS127445
Ramelteon TAK-375
RITA (NSC 652287)
Rocilinostat(ACY-1215)
Retigabine (Ezogabine)
RGW 611
Remodelin hydrobromide
Ruxolitinib (INCB-18424) phosphate
RKI 1447
R406
Riociguat
RN486
R-428
Ramoplanin
SU5402
Selamectin
STF-118804
SRT3109
Sermorelin acetate
Sch 527123
SC 26196
SB-239063
SP 600125
SNS-032
SB 743921
SGC 0946 SGC-0946
SU11272
SKI II (SphK-I2)
SGX-523
SL 327
SB 242084
SB715992 Ispinesib
Somatostatin
SB715992 Ispinesib
SC-144
Semagacestat (LY450139)
SEP-0372814
Sunitinib malate
SKLB 610;SKLB610
SB 431542
SGI-1776
SMI-4a
StemRegenin 1(SR1)
SCR7
sitafloxacin isomer III(RRS)
sitafloxacin isomer I(SSR)
SCH 900776
sitafloxacin isomer II(RSR)
SB 525334
SB-505124
SB 271046 hydrochloride
SCH772984
Selinexor (KPT-330)
SU9516
SL251188
SB-737050-A
Salubrinal
SB 408124
SB 202190SB202190 (FHPI)
Staurosporine
Tamsulosin hydrochloride
Tipifarnib (Zarnestra)
Tasosartan
Torcetrapib (CP-529414)
Telmesteine
TAME
Telatinib
TH-302
TTP 22
Torin 1
Tandutinib (MLN518)
Teneligliptin
Tozadenant;SYN-115
Telaprevir
Thiazovivin
Tasisulam sodium LY-573636
TGX 221
THIACETAZONE
Tacrolimus
Tenovin-1
TOK-001
TMC-207
THZ1 Hydrochloride
TPT-260 , NSC55712
TCS JNK 5a(JNK Inhibitor IX) SC-202671
Triptorelin acetate
Thymosin beta 4 acetate
Tenovin-3
TMP269
tert-butyl(((3aR,4R,6aR)-5-fluoro-2,2-dimethyl-6-((trityloxy)methyl)-4,6a-dihydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)diphenylsilane
Tyrosine kinase inhibitor
TAK 632;TAK-632;TAK632
Tenovin 6;Tenovin-6
TPCA-1
TGR5
TAK-715
TAK-875
TWS 119
TRX818 sodium
Teniposide
Tasquinimod
Tirasemtiv(CK 2017357)
Temocapril hydrochloride
TP-808
Trelagliptin
Ticagrelor
Torin 2
TAS-103(BMS-247615)
TRV130 hydrochloride
T 0901317
TAK-063;TAK063
TAK-438
T-1095 ;T 1095; T1095
Thymosin alpha 1
URMC-099
URB 754
URB597
UNC 1215;UNC1215;UNC-1215
UK 383367
VX-745
VX 770
Vidofludimus(4SC-101; SC12267)
VU 0364439
Vilazodone
VX-809
Vinpocetine
Verteporfin
Voriconazole
Vindesine sulfate
VRT752271
VS-5584 SB-2343; VS5584; VS 5584; SB2343; SB 2343
Vortioxetine hydrobroMide
VTP27999 HCL
VU 0357121
Vitamin D4
VU 0361737
VX 222
WHIP-154
WZ4003
WS3;WS-3;WS 3
WZ 811
WAY-100635 maleate salt
WS6;WS-6;WS-6
WIN 55212-2 mesylate
WH-4-023
WAY-362450(XL335, FXR-450)
XL019
XEN445
XL-765, SAR245409
XMD 8-92
XMD17-109
XL388
YM 155
YS-49
Y 27632 dihydrochloride
Y320;Y-320
YK 4-279
YM90Khydrochloride
Y27632
Zonisamide sodium salt
ZM323881
Z-JIB-04 (NSC 693627)
ZLN005
ZM 241385
Zibotentan
Zotarolimus A179578 ABT 578
ZSTK 474
[2,8-Bis(trifluoromethyl)-4-quinolinyl]-2-pyridinylmethanone
 

None of the products will be supplied to countries in which this could be in conflict with the existing patents. However the final responsibility lies with the Buyer.
 
Homepage | About Us | Products | News&Events | Custom Synthesis | Order Infomation | Contact Us
Friendly link: molbase   Copyright © Taizhou Crene Biotechnology Co.,Ltd. 技术支持:趋势科技