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   CAS NO.    Products Name
   935881-37-1 AR-42  more...
   AR-42 is a novel HDAC inhibitor with an IC50 of 0.61 μM for acute lymphoblastic leukemia (697) cell lines.In chronic lymphocytic leukemia (CLL) cells, the 48-hr LC50 of AR-42 is 0.76 μ...
   414864-00-9 Belinostat (PXD101)  more...
   Belinostat (PXD101) is a novel hydroxamate-type inhibitor of histone deacetylase (HDAC) activity. Belinostat inhibits HDAC activity in HeLa cell extracts with an IC50 of 27 nM. PXD101 i...
   1012054-59-9 CUDC-101  more...
   CUDC-101 is a potent multitargeted HDAC, EGFR and HER2 inhibitor with IC50 of 4.4, 2.4, and 15.7 nM, respectively. CUDC-101 has novel structure incorporating HDAC inhibitory functionali...
   209783-80-2 Entinostat (MS-275, SNDX-275)  more...
   Entinostat (MS-275, SNDX-275) is a potent HDAC inhibitor with IC50 of 0.3 and 8µM for HDAC1 and HDAC3, respectively. Entinostat (MS-275, SNDX-275) is synthetic benzamide derivativ...
   732302-99-7 ITF2357 (Givinostat)  more...
   ITF2357 (Givinostat) is a potent inhibitor of HDAC with IC50 of 7.5-16 nM....
   726169-73-9 MGCD0103 (Mocetinostat)  more...
   MGCD0103 (Mocetinostat) is a potent HDAC inhibitor with IC50 of 0.15, 0.29 and 1.66 μM for HDAC 1, HDAC 2 and HDAC 3, respectively. In intact cells, MGCD0103 inhibited only a fraction o...
   783355-60-2 PCI 24781  more...
   PCI-24781 (CRA-024781) is a novel broad spectrum hydroxamic acid-based inhibitor of histone deacetylase (HDAC) that shows antitumor activity in vitro and in vivo preclinically and is un...
   404950-80-7 Panobinostat  more...
   A novel broad-spectrum HDAC(histone deacetylase) inhibitor belongs to the hydroxamate class, in Philadelphia chromosome–negative (Ph-) acute lymphoblastic leukemia (ALL). Histone deace...
   929016-96-6 SB939 (Pracinostat)  more...
   SB939 is a novel potent and orally active histone deacetylase inhibitor with an IC50 of 52 nM for HDAC1 and a GI50 of 0.56 µM for Colo205. Its IC50 for HCT-116 colon cancer cell l...
   1310693-92-5 Tubastatin A HCl  more...
   Tubastatin A is substantially selective for all 11 HDAC isoforms and maintains over 1000-fold selectivity against all isoforms excluding HDAC8, where it has approximately 57-fold select...

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