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OMadacycline (tosylate)

OMadacycline (tosylate) 1075240-43-5
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Chemical Information
Product name:OMadacycline (tosylate) Purity:NLT98%
CAS NO:1075240-43-5 Solubility:
Molecular Formula:C36H48N4010S Package:Customizable upon request
Molecular Weight:728.86 Storage:4°C, protect from light
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Remarks
Omadacycline tosylate is a semisynthetic tetracycline-class antibacterial agent, which has been designated by some as a “new-generation tetracycline” or “the first in a new class of aminomethylcyclines.” Omadacycline has been structurally modified to provide effectiveness against certain strains of bacteria that have mechanisms to resist the action of older tetracyclines. The new agent binds to the 30S ribosomal unit, blocks bacterial protein synthesis, and is generally bacteriostatic[1]. Omadacycline tosylate has broad-spectrum antibacterial activity against aerobic and anaerobic Gram-positive and Gram-negative bacteria, as well as atypical bacteria. Omadacycline tosylate has been studied in acute bacterial skin and skin structure infections, community-acquired pneumonia and urinary tract infections.
References
[1] DANIEL A. HUSSAR; Elias B C. Omadacycline tosylate, Sarecycline hydrochloride, Rifamycin sodium, and Moxidectin[J]. Journal of the American Pharmacists Association, 2019. DOI:10.1016/j.japh.2019.07.016.
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