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Findings increasingly suggest the mortality risk may be reduced by initiating daptomycin within 3 days of infection. Daptomycin (Cubicin) is a cyclic lipopeptide antibiotic with broad-spectrum gram-positive activity, including methicillin-resistant Staphyloc..
On July 6, 2021 Alvotech announced the start of a comparative, confirmatory efficacy and safety clinical study comparing AVT04, Alvotech’s proposed ustekinumab biosimilar, to the reference product STELARA, in patients with moderate-to-severe chronic plaque ps..
August 5, 2021Jonathan Alicea Outlook Therapeutics anticipates submitting a Biologics License Application to the FDA as early as next year. Yesterday, Outlook Therapeutics announced findings from the NORSE 2 trial of bevacizumab-vikg (LYTENAVA) for wet age..
Real-world data show that similar treatment outcomes were achieved with ustekinumab and TNF inhibitors in those with psoriatic arthritis.Psoriatic arthritis (PsA) is a chronic, immune-mediated disease which affects around 22% of those with psoriasis. PsA..
Researchers discover an unexpected link between DNA winding and metabolism in the gut to ameliorate ageing Our genetic material is stored in our cells in a specific way to make the meter-long DNA molecule fit into the tiny cell nucleus of each body cell. An ..
1. Overall survival and progression-free survival were higher for patients on nivolumab plus chemotherapy compared to chemotherapy alone.2. Severe adverse events occurred more frequently in the nivolumab group and more patients withdrew from treatment due to..
Final data from a phase 3 trial assessing evolocumab in patients with HIV who have high cholesterol confirmed the safety and efficacy of the drug as a treatment. Final data from the phase 3 BEIJERINCK trial assessing evolocumab (Repatha, Amgen) in patients liv..
A post-hoc analysis of the AWARD-11 trial indicates that 4.5 mg of dulaglutide was effective in lowering and maintaining A1C levels <7% regardless of baseline levels. A post-hoc analysis of the AWARD-11 trial showed that higher doses of dulaglutide were h..
Lubiprostone was not significantly more effective compared with placebo in children or adolescents with pediatric functional constipation; however, the safety profile was similar to that in adults, according to study results.“In summary, the results of this a..
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