ACH-0141625 Sovaprevir

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Chemical Information

Product name：ACH-0141625 Sovaprevir	Purity：98% min
CAS NO：1001667-23-7	Solubility：Soluble in DMSO
Molecular Formula：C₄₃H₅₃N₅O₈S	Package：Package according to customer requirements
Molecular Weight：799.975	Storage：Store at -20℃

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Remarks

Sovaprevir is a nonstructural 3 (NS3) protease inhibitor potentially for the treatment of HCV infection.

Synonyms:

(2S,4R)-N-((1R,2S)-1-((Cyclopropylsulfonyl)carbamoyl)-2-ethenylcyclopropyl)-1-((2S)-3,3-dimethyl-2-(2-oxo-2-(piperidin-1-yl)ethyl)butanoyl)-4-((7-methoxy-2-phenylquinolin-4-yl)oxy)pyrrolidine-2-carboxamide;

(2S,4R)-1-((S)-2-tert-butyl-4-oxo-4-(piperidin-1-yl)butanoyl)-N-((1R,2S)-1-(cyclopropylsulfonylcarbamoyl)-2-vinylcyclopropyl)-4-(7-methoxy-2-phenylquinolin-4-yloxy)pyrrolidine-2-carboxamide;

References

1: De Clercq E. Current race in the development of DAAs (direct-acting antivirals) against HCV. Biochem Pharmacol. 2014 Jun 15;89(4):441-52. doi: 10.1016/j.bcp.2014.04.005. PubMed PMID: 24735613.

2: Vere Hodge RA. Meeting report: 26th International Conference on Antiviral Research. Antiviral Res. 2013 Oct;100(1):276-85. doi: 10.1016/j.antiviral.2013.08.006. PubMed PMID: 23973733.