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RG3039 1005504-62-0
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Chemical Information
Product name:RG3039 Purity:98% min
CAS NO:1005504-62-0 Solubility:Soluble in DMSO
Molecular Formula:C21H23Cl2N5O Package:Package according to customer requirements
Molecular Weight:432.346 Storage:Store at -20℃
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RG3039, also known as PF-06687859, is a potent DcpS inhibitor. DcpS is a therapeutic target for spinal muscular atrophy. Spinal muscular atrophy (SMA) is caused by deletion or mutation of both copies of the SMN1 gene which produces an essential protein known as SMN. RG3039 improves motor function in SMA mice. RG3039 also showed activity to improve survival, function and motor unit pathologies in two SMA mouse models.
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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