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Silmitasertib

Silmitasertib 1009820-21-6
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Chemical Information
Product name:Silmitasertib Purity:98% min
CAS NO:1009820-21-6 Solubility:DMSO : ≥ 35 mg/mL (100.07 mM)
Molecular Formula:C19H12ClN3O2 Package:Package according to customer requirements
Molecular Weight:349.770 Storage:Store at -20℃
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Remarks

Silmitasertib, also know as CX-4945, is an orally bioavailable small-molecule inhibitor of CK2 with potential antineoplastic activity. CK2 inhibitor CX-4945 selectively binds to and inhibits the enzyme casein kinase II (CK2), which may lead to an inhibition of cellular proliferation. CK2, a protein kinase often overexpressed in a variety of cancer cell types, appears to be correlated with malignant transformation, tumor growth and survival.

 

Synonyms:

5-((3-Chlorophenyl)amino)benzo[c][2,6]naphthyridine-8-carboxylic acid;

CX-4945;

Benzo[c]-2,6-naphthyridine-8-carboxylic acid, 5-[(3-chlorophenyl)amino]-;

5-(3-chloroanilino)benzo[c][2,6]naphthyridine-8-carboxylic acid;

 

Properties:

Density: 1.491 g/cm3

Boiling Point: 568.45ºC at 760 mmHg

Flash Point: 297.588ºC

 

 

 

Casein Kinase Inhibitor Related Prodcuts:

LY294002; LY364947; IWP-2; TTP 22; SR-3029

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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