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MK-8245 1030612-90-8
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Chemical Information
Product name:MK-8245 Purity:98% min
CAS NO:1030612-90-8 Solubility:DMSO: 19 mg/mL
Molecular Formula:C17H16BrFN6O4 Package:Package according to customer requirements
Molecular Weight:467.249 Storage:Store at -20℃
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MK-8245 is a potent, liver-targeted SCD inhibitor with preclinical antidiabetic and antidyslipidemic efficacy with a significantly improved therapeutic window. MK-8245 was believed to inhibit the SCD enzyme solely in the liver and not in other tissues for the following reasons. When SCD inhibition has been measured by desaturation index in tissues of rodents treated with MK-8245, the desaturation index was significantly reduced in liver but not in other tissues such as skin, eye and adipose tissue.

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