Peramivir Trihydrate

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Chemical Information

Product name：Peramivir Trihydrate	Purity：98% min
CAS NO：1041434-82-5	Solubility：H2O : 6.6 mg/mL (17.26 mM)
Molecular Formula：C₁₅H₃₄N₄O₇	Package：Package according to customer requirements.
Molecular Weight：382.4530	Storage：Store at -20℃

Quality control

COA

Remarks

Peramivir trihydrate (RWJ-270201 trihydrate;BCX-1812 trihydrate) is a highly potent, selective and orally active influenza virus neuraminidase (NA) inhibitor, with IC50 values ranging from 0.9 to 4.3 nM for nine NA subtypes.

References

[1]. Louie JK, Yang S, Yen C, Acosta M, Schechter R, Uyeki TM. Use of Intravenous Peramivir for Treatment of Severe Influenza A(H1N1)pdm09. PLoS One. 2012;7(6):e40261.

[2]. Sakata H. Clinical efficiency in children treated with intravenous drip infusion of peramivirJpn J Antibiot. 2011 Dec;64(6):383-7.

[3]. Abed Y, Pizzorno A, Boivin G. Therapeutic Activity of Intramuscular Peramivir in Mice Infected with a Recombinant Influenza A/WSN/33 (H1N1) Virus Containing the H275Y Neuraminidase Mutation. Antimicrob Agents Chemother. 2012 Aug;56(8):4375-80.