SB 242084 hydrochloride

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Chemical Information

Product name：SB 242084 hydrochloride	Purity：98% min
CAS NO：1049747-87-6	Solubility：DMSO : ≥ 125.5 mg/mL (268.29 mM)
Molecular Formula：C₂₁H₂₁Cl₃N₄O₂	Package：Package according to customer requirements.
Molecular Weight：394.854	Storage：Store at -20 ℃

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Remarks

SB 242084 hydrochloride is a 5-HT2C receptor antagonist(pKi=9.0) that displays 158- and 100-fold selectivity over 5-HT2A and 5-HT2B receptors respectively.

References

[1]. Kennett GA, et al. SB 242084, a selective and brain penetrant 5-HT2C receptor antagonist. Neuropharmacology. 1997 Apr-May;36(4-5):609-20.

[2]. Bromidge SM, et al. 6-Chloro-5-methyl-1-[[2-[(2-methyl-3-pyridyl)oxy]-5-pyridyl]carbamoyl]- indoline (SB-242084): the first selective and brain penetrant 5-HT2C receptor antagonist. J Med Chem. 1997 Oct 24;40(22):3494-6.