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Tacrolimus (FK506)

Tacrolimus (FK506) 104987-11-3
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Chemical Information
Product name:Tacrolimus (FK506) Purity:98%min
CAS NO:104987-11-3 Solubility:DMSO : ≥ 28 mg/mL (34.83 mM)
Molecular Formula:C44H69NO12 Package:Packaging according to customer requirements
Molecular Weight:804.02 Storage:Store at -20℃
Quality control

Tacrolimus (FK506, FR900506, Fujimycin, Prograf) is a 23-membered macrolide lactone, it reduces peptidyl-prolyl isomerase activity in T cells by binding to the immunophilin FKBP12 (FK506 binding protein) creating a new complex. Tacrolimus also inhibits the phosphatase activity of calcineurin. Tacrolimus induces vascular endothelial autophagy.



Appearance & Physical State: White or off-white crystalline powder

Density: 1.19 g/cm3

Boiling Point: 871.7ºC at 760 mmHg

Melting Point: 113-115ºC

Flash Point: 481ºC

Refractive Index: 1.549

Storage Condition: -20ºC

Vapor Pressure: 1.73E-35mmHg at 25°C




Related Products:  

Everolimus; Temsirolimus; PI-103; Torin 1; PF-04691502; Apitolisib; Torin 2; BGT226; Palomid 529; Deforolimus; KU-0063794; Rapamycin; Tacrolimus monohydrate

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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