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Eplerenone, also known as Inspra and CGP-30083, is a selective aldosterone receptor antagonist used to treat hypertension and congestive heart failure. Eplerenone provides marked protection against vascular injury in the kidney and heart.
[1]. Chatterjee, S., et al., Eplerenone is not superior to older and less expensive aldosterone antagonists. Am J Med, 2012. 125(8): p. 817-25.
[2]. Dhillon, S., Eplerenone: a review of its use in patients with chronic systolic heart failure and mild symptoms. Drugs, 2013. 73(13): p. 1451-62.
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