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Product :

FIT-039

FIT-039 1113044-49-7
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Chemical Information
Product name：FIT-039 Purity：98% min
CAS NO：1113044-49-7 Solubility：
Molecular Formula：C17H18FN3S Package：Package according to customer requirements
Molecular Weight：315.41 Storage：-20℃
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Remarks

FIT-039 is a selective, ATP-competitive and orally active CDK9 inhibitor with an IC50 of 5.8 μM for CKD9/cyclin T1. FIT-039 does not inhibit other CDKs and other kinases. FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 μM), HSV-2, human adenovirus, and human CMV. FIT-039 is a promising antiviral agent for inhibiting drug-resistant HSVs and other DNA viruses.

References
[1]. Makoto Yamamoto, et al. CDK9 Inhibitor FIT-039 Prevents Replication of Multiple DNA Viruses. J Clin Invest. 2014 Aug;124(8):3479-88.
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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