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AZ-3146

AZ-3146 1124329-14-1
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Chemical Information
Product name:AZ-3146 Purity:98% min
CAS NO:1124329-14-1 Solubility:DMSO : 11.75 mg/mL (25.96 mM)
Molecular Formula:C24H32N6O3 Package:Packaging according to customer requirements
Molecular Weight:452.549 Storage:Store at -20℃
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Remarks
AZ3146 is a novel and potent Mps1 inhibitor, which was used to probe the role of Mps1's catalytic activity during mitosis. AZ3146 also inhibits FAK, JNK1, JNK2, KSP and Kit. In in vitro kinase assays, AZ3146 inhibited human Mps1Cat with an IC50 (50% inhibitory concentration) of ~35 nM. AZ3146 also efficiently inhibited autophosphorylation of full-length Mps1 immunoprecipitated from human cells.
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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