Calcipotriol, a synthetic derivative of calcitriol or Vitamin D, is used in the treatment of psoriasis and marketed under the trade name Dovonex. It has comparable affinity with calcitriol (Vit. D) for the Vitamin D receptor (VDR), while being less than 1% as active as the calcitriol in regulating calcium metabolism. Chronic plaque psoriasis is the chief medical use of calcipotriol. It has also been used successfully in the treatment of alopecia areata.
Properties:
Appearance & Physical State: white crystalline solid
Density: 1.12g/cm3
Melting Point: 166-168ºC
Boiling Point: 582ºC at 760mmHg
Flash Point: 250.6ºC
Refractive Index: 1.579
Storage Condition: Store in original container in a cool dark place.
Vapor Pressure: 5.74E-16mmHg at 25°C
Related Products:
Calcipotriol; Calcipotriol monohydrate; Calcipotriol Intermediate(112849-17-9; 112849-27-1; 128387-35-9)