Fondaparinux sodium

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Chemical Information

Product name：Fondaparinux sodium	Purity：98% min
CAS NO：114870-03-0	Solubility：H2O : ≥ 30 mg/mL (17.26 mM)
Molecular Formula：C₃₁H₄₃N₃Na₁₀O₄₉S₈	Package：Package according to customer requirements
Molecular Weight：1728.08	Storage：Store at 2-8°C

Quality control

COA

Remarks

Fondaparinux is a synthetic glucopyranoside with antithrombotic activity. It selectively binds to antithrombin III, thereby potentiating the innate neutralization of activated factor X (Factor Xa) by antithrombin; a synthetic inhibitor of Factor Xa.

Fondaparinux sodium is a factor Xa inhibitor to form the high affinity binding site for the anti-coagulant factor antithrombin III (ATIII).

Factor Xa Related Products:

Apixaban; Rivaroxaban; Betrixaban; Edoxaban tosylate; Milvexian

References

[1]. Bauer KA. et al. Fondaparinux sodium: a selective inhibitor of factor Xa. Am J Health Syst Pharm. 2001 Nov 1;58 Suppl 2:S14-7.

[2]. Ben-Hadj-Khalifa S, et al. Differential coagulation inhibitory effect of fondaparinux, enoxaparin and unfractionated heparin in cell models of thrombin generation. Blood Coagul Fibrinolysis. 2011 Jul;22(5):369-73.