Product :
GLYX-13 Rapastinel
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Chemical Information
| Product name：GLYX-13 Rapastinel |
Purity：98% min |
| CAS NO：117928-94-6 |
Solubility：DMSO : ≥ 32 mg/mL (77.39 mM) |
| Molecular Formula：C18H31N5O6 |
Package：Package according to customer requirements |
| Molecular Weight：413.469 |
Storage：Store at -20℃ |
Remarks
Rapastinel, also known as GLYX-13 and BV-102, is a novel antidepressant drug approved as an adjunctive therapy for the treatment of treatment-resistant major depressive disorder. It is a centrally active, intravenously administered (non-orally active) amidated tetrapeptide (Thr-Pro-Pro-Thr-NH2) that acts as a selective, weak partial agonist (mixed antagonist/agonist) of an allosteric site at the glycine site of the NMDA receptor complex (Emax ≈ 25%).[1][2] The drug is a rapid-acting and long-lasting antidepressant as well as robust cognitive enhancer by virtue of its ability to both inhibit and enhance NMDA receptor-mediated signal transduction.