BGC-20-1531

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Chemical Information

Product name：BGC-20-1531	Purity：98% min
CAS NO：1186532-61-5	Solubility：
Molecular Formula：C₂₆H₂₃N₂NaO₆S	Package：Package according to customer requirements
Molecular Weight：514.525	Storage：-20 ℃

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Remarks

BGC201531, also known as GTPL3380 and AP-1531, is a EP4 antagonist for the treatment of acute migraine.

References

1: Antonova M, Wienecke T, Maubach K, Thomas E, Olesen J, Ashina M. The pharmacological effect of BGC20-1531, a novel prostanoid EP4 receptor antagonist, in the prostaglandin E2 human model of headache. J Headache Pain. 2011 Oct;12(5):551-9. doi: 10.1007/s10194-011-0358-9. Epub 2011 Jun 17. PubMed PMID: 21681585; PubMed Central PMCID: PMC3173651.

2: Maubach KA, Davis RJ, Clark DE, Fenton G, Lockey PM, Clark KL, Oxford AW, Hagan RM, Routledge C, Coleman RA. BGC20-1531, a novel, potent and selective prostanoid EP receptor antagonist: a putative new treatment for migraine headache. Br J Pharmacol. 2009 Jan;156(2):316-27. doi: 10.1111/j.1476-5381.2009.00027.x. Epub 2009 Jan 19. PubMed PMID: 19154437; PubMed Central PMCID: PMC2697835.