ML-109

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Chemical Information

Product name：ML-109	Purity：98% min
CAS NO：1186649-91-1	Solubility：DMSO : 83.33 mg/mL (159.15 mM)
Molecular Formula：C₃₁H₂₉N₃O₅	Package：Package according to customer requirements.
Molecular Weight：523.579	Storage：-20 ℃

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Remarks

ML-109 is a potent and full thyroid stimulating hormone receptor (TSHR) agonist, with an EC50 of 40 nM.

Chemical Name:

N-(4-(5-(3-Benzyl-5-hydroxy-4-oxo-1,2,3,4-tetrahydroquinazolin-2-yl)-2-methoxybenzyloxy)phenyl)acetamide

References

[1]. Neumann S, et al. Small-molecule agonists for the thyrotropin receptor stimulate thyroid function in human thyrocytes and mice. Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12471-6.