Product :
Delpazolid (LCB01-0371)
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Chemical Information
Product name:Delpazolid (LCB01-0371) |
Purity:99% min |
CAS NO:1219707-39-7 |
Solubility:DMSO : 30 mg/mL (97.30 mM) |
Molecular Formula:C14H17FN4O3 |
Package:Package according to customer requirements |
Molecular Weight:308.308 |
Storage:Store at -20℃ |
Remarks
Delpazolid, also known as LCB01-0371, is a new oxazolidinone with cyclic amidrazone. In vitro activity of LCB01-0371 against 624 clinical isolates was evaluated and compared with those of linezolid, vancomycin, and other antibiotics. LCB01-0371 showed good activity against Gram-positive pathogens. In vivo activity of LCB01-0371 against systemic infections in mice was also evaluated. LCB01-0371 was more active than linezolid against these systemic infections. LCB01-0371 showed bacteriostatic activity against Staphylococcus aureus.