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SetmEegenin 1

SetmEegenin 1 1227633-49-9
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Chemical Information
Product name：SetmEegenin 1 Purity：98% min
CAS NO：1227633-49-9 Solubility：DMSO : ≥ 33 mg/mL (76.83 mM)
Molecular Formula：C24H23N5OS Package：Package according to customer requirements
Molecular Weight：429.537 Storage：Store at -20℃
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Remarks
SetmEegenin 1 is a purine derivative that antagonizes aryl hydrocarbon receptor signaling with an IC50 value of 127 nM in CD34+ cells, which results in sustained expression of CD34.
References

[1]. Boitano AE, et al. Aryl Hydrocarbon Receptor Antagonists Promote the Expansion of Human Hematopoietic Stem Cells. Science. 2010 Sep 10;329(5997):1345-8.

[2]. Gao H, et al. Suppression of homeobox transcription factor VentX promotes expansion of human hematopoietic stem/multipotent progenitor cells. J Biol Chem. 2012 Aug 24;287(35):29979-87.

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