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Product :

kb NB 142-70

kb NB 142-70 1233533-04-4
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Chemical Information
Product name:kb NB 142-70 Purity:98% min
CAS NO:1233533-04-4 Solubility:DMSO : ≥ 33 mg/mL (131.31 mM)
Molecular Formula:C11H9NO2S2 Package:Package according to customer requirements
Molecular Weight:251.325 Storage:Store at -20℃
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Remarks

kb NB 142-70 is a selective protein kinase D (PKD) inhibitor with IC50 values are 28.3, 58.7 and 53.2 nM for PKD1, 2 and 3 respectively. kb NB 142-70 prevents wound-induced migration of intestinal epithelial cells. PKD1, the most studied member of the PKD family, is implicated in the regulation of a remarkable array of fundamental biological processes, including signal transduction, cell proliferation and differentiation, membrane trafficking, hormone secretion, immune regulation, cardiac hypertrophy, angiogenesis, and cancer.

 

 

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