AZD-1722 Tenapanor

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Chemical Information

Product name：AZD-1722 Tenapanor	Purity：99% min
CAS NO：1234423-95-0	Solubility：DMSO : 50 mg/mL (43.67 mM)
Molecular Formula：C₅₀H₆₆Cl₄N₈O₁₀S₂	Package：Package according to customer requirements
Molecular Weight：1145.05	Storage：Store at -20℃

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Remarks

Tenapanor, also known as AZD-1722 and RDX 5791, is an inhibitor of the sodium-proton (Na(+)/H(+)) exchanger NHE3, which plays a prominent role in sodium handling in the gastrointestinal tract and kidney. Tenapanor possesses an excellent preclinical safety profile and, as of now, there are no serious concerns about its side effects.

References

[1]. Spencer AG, et al. Intestinal inhibition of the Na+/H+ exchanger 3 prevents cardiorenal damage in rats and inhibitsNa+ uptake in humans.