Pirodavir

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Chemical Information

Product name：Pirodavir	Purity：98% min
CAS NO：124436-59-5	Solubility：DMSO : 10 mg/mL (27.07 mM)
Molecular Formula：C₂₁H₂₇N₃O₃	Package：Package according to customer requirements
Molecular Weight：369.457	Storage：Store at -20℃

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Remarks

Pirodavir, also known as R 77975, is a capsid-binding antipicornavirus agent with potent in vitro activity against both group A and group B rhinovirus serotypes. Pirodavir was one of the most promising capsid-binding compounds to show efficacy in human clinical trials for chemoprophylaxis of the common cold.

References

[1]. Barnard DL, et al. In vitro activity of expanded-spectrum pyridazinyl oxime ethers related to pirodavir: novel capsid-binding inhibitors with potent antipicornavirus activity. Antimicrob Agents Chemother. 2004 May;48(5):1766-72.

[2]. Andries K, et al. In vitro activity of pirodavir (R 77975), a substituted phenoxy-pyridazinamine with broad-spectrum antipicornaviralactivity. Antimicrob Agents Chemother. 1992 Jan;36(1):100-7.