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Dorzolomide hydrochloride

Dorzolomide hydrochloride 130693-82-2
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Chemical Information
Product name:Dorzolomide hydrochloride Purity:98% min
CAS NO:130693-82-2 Solubility:DMSO : < 1 mg/mL
Molecular Formula:C10H17ClN2O4S3 Package:Package according to customer requirements
Molecular Weight:360.901 Storage:Store at -20℃
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Remarks

Dorzolamide (trade name Trusopt) is a carbonic anhydrase inhibitor. It is an anti-glaucoma agent and topically applied in the form of eye drops. This drug, developed by Merck, was the first drug in human therapy (market introduction 1995) which resulted from structure-based drug design. Dorzolamide hydrochloride is used to lower increased intraocular pressure in open-angle glaucoma and ocular hypertension. The combination of dorzolamide with timolol is marketed under the trade name Cosopt.

Dorzolamide HCl is a water-soluble, potent inhibitor of human carbonic anhydrase II and IV with Ki of 1.9 nM and 31 nM, respectively, used as anti-glaucoma agent.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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