MDL-29951

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Chemical Information

Product name：MDL-29951	Purity：98% min
CAS NO：130798-51-5	Solubility：DMSO : ≥ 50 mg/mL (165.50 mM)
Molecular Formula：C₁₂H₉Cl₂NO₄	Package：Package according to customer requirements
Molecular Weight：302.110	Storage：Store at -20℃

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Remarks

MDL-29951 is a novel glycine antagonist of NMDA receptor activation (Ki=0.14 mM, [3H]glycine binding) in vitro and in vivo.

References

[1]. Baron BM, et al. Potent indole- and quinoline-containing N-methyl-D-aspartate antagonists acting at the strychnine-insensitive glycine binding site. J Pharmacol Exp Ther. 1992 Sep;262(3):947-56.

[2]. Wright SW, et al. 3-(2-carboxyethyl)-4,6-dichloro-1H-indole-2-carboxylic acid: an allosteric inhibitor of fructose-1,6-bisphosphatase at the AMP site. Bioorg Med Chem Lett. 2003 Jun 16;13(12):2055-8.