CYM2503

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Chemical Information

Product name：CYM2503	Purity：98% min
CAS NO：1308833-36-4	Solubility：
Molecular Formula：C₄₅H₅₅N₅O₇	Package：Package according to customer requirements
Molecular Weight：777.947	Storage：-20℃

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Remarks

CYM2503 is a positive allosteric modulator (PAM) of the GAL2 receptor which potentiates galanin-induced IP1 production in vitro. The compound has no affinity for the orthosteric galanin binding site of the receptor (as measured by its inability to displace iodinated galanin, or to induce IP1 accumulation on its own).

References

1: Lu X, Roberts E, Xia F, Sanchez-Alavez M, Liu T, Baldwin R, Wu S, Chang J, Wasterlain CG, Bartfai T. GalR2-positive allosteric modulator exhibits anticonvulsant effects in animal models. Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15229-34. doi: 10.1073/pnas.1008986107. PubMed PMID: 20660766; PubMed Central PMCID: PMC2930524.