Welcome to Crene Biotechnology!

+86-576-88205808

Product :

Ro 25-6981 Maleate

Ro 25-6981 Maleate  1312991-76-6
Size Price Stock Quantity
Get Quotation Now Add to Cart Bulk Inquiry
Shipping and handling fee USD40, Free delivery is qualified when the total value of your order exceeds USD500.If the item is temporarily out of stock. Please email to order@pharm-intermediates.com,we will inform you when we have it in stock.
Chemical Information
Product name:Ro 25-6981 Maleate Purity:98% min
CAS NO:1312991-76-6 Solubility:DMSO : ≥ 61 mg/mL (133.91 mM)
Molecular Formula:C26H33NO6 Package:Package according to customer requirements
Molecular Weight:455.543 Storage:Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Quality control
Remarks
Ro 25-6981 maleate is a highly potent and selective blocker of N-methyl-D-aspartate receptors containing the NR2B subunit. Ro 25-6981 inhibited 3H-MK-801 binding to rat forebrain membranes in a biphasic manner with IC50 values of 0.003 microM and 149 microM for high- (about 60%) and low-affinity sites, respectively. NMDA receptor subtypes expressed in Xenopus oocytes were blocked with IC50 values of 0.009 microM and 52 microM for the subunit combinations NR1C & NR2B and NR1C & NR2A, respectively, which indicated a >5000-fold selectivity.
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
Friendly link:

Copyright Copyright (C) 2018-2021 Taizhou Crene Biotechnology Co.,Ltd.  

Address:Economic Developed Zone of Taizhou Zhejiang China