Atorvastatin Calcium

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Chemical Information

Product name：Atorvastatin Calcium	Purity：98% min
CAS NO：134523-01-6	Solubility：Soluble in DMSO
Molecular Formula：C₃₃H₃₄FN₂NaO₅	Package：Package according to customer requirements
Molecular Weight：580.622	Storage：Store at -20℃

Quality control

COA

Remarks

Atorvastatin sodium is a competitive inhibitor of HMG-CoA reductase, increasing expression of low-density lipoprotein receptors (LDL receptors) on hepatocytes. Atorvastatin sodium pretreatment attenuates ischemic brain edema by suppressing aquaporin 4.

References

1: Wang Y, Jin Y, Yun X, Wang M, Dai Y, Xia Y. Co-administration with simvastatin or lovastatin alters the pharmacokinetic profile of sinomenine in rats through cytochrome P450-mediated pathways. Life Sci. 2018 Aug 7. pii: S0024-3205(18)30458-2. doi: 10.1016/j.lfs.2018.08.012. [Epub ahead of print] PubMed PMID: 30096386.

2: Cheng ZJ, Dai TM, Shen YY, He JL, Li J, Tu JL. Atorvastatin Pretreatment Attenuates Ischemic Brain Edema by Suppressing Aquaporin 4. J Stroke Cerebrovasc Dis. 2018 Aug 6. pii: S1052-3057(18)30380-X. doi: 10.1016/j.jstrokecerebrovasdis.2018.07.011. [Epub ahead of print] PubMed PMID: 30093197.