Product :
Cabazitaxel N-1
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Chemical Information
| Product name：Cabazitaxel N-1 |
Purity：98% min |
| CAS NO：1354900-66-5 |
Solubility：Soluble in DMSO |
| Molecular Formula：954.065 |
Package：Package according to customer requirements |
| Molecular Weight：954.065 |
Storage：Store at -20℃ |
Remarks
Cabazitaxel is a semi-synthetic derivative of the natural taxoid 10-deacetylbaccatin III with potential antineoplastic activity. Cabazitaxel binds to and stabilizes tubulin, resulting in the inhibition of microtubule depolymerization and cell division, cell cycle arrest in the G2/M phase, and the inhibition of tumor cell proliferation. Unlike other taxane compounds, this agent is a poor substrate for the membrane-associated, multidrug resistance (MDR), P-glycoprotein (P-gp) efflux pump and may be useful for treating multidrug-resistant tumors. In addition, cabazitaxel penetrates the blood-brain barrier (BBB).