Ajulemic acid

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Chemical Information

Product name：Ajulemic acid	Purity：98% min
CAS NO：137945-48-3	Solubility：
Molecular Formula：C₂₅H₃₆O₄	Package：Package according to customer requirements.
Molecular Weight：400.551	Storage：-20 ℃

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Remarks

Ajulemic acid, also known as lenabasum, is a cannabinoid CB2 agonist potentially for treatment of skin-predominant dermatomyositis. Ajulemic acid is a synthetic cannabinoid derivative of the non-psychoactive THC metabolite 11-nor-9-carboxy-THC that shows useful analgesic and anti-inflammatory effects without causing a subjective "high". It is being developed for the treatment of neuropathic pain and inflammatory conditions such as arthritis. It does not however share the anti-emetic effects of other cannabinoids but may be useful for treating pain and chronic inflammatory conditions where nausea is not present.

Properties:

Density: 1.085g/cm3

Boiling Point:495.7ºC at 760mmHg

Flash Point: 158.5ºC

Refractive Index: 1.535

Vapor Pressure: 1.2E-10mmHg at 25°C

References

1: Zurier RB, Burstein SH. Cannabinoids, inflammation, and fibrosis. FASEB J. 2016 Jul 19. pii: fj.201600646R. [Epub ahead of print] Review. PubMed PMID: 27435265.

2: Lucattelli M, Fineschi S, Selvi E, Garcia Gonzalez E, Bartalesi B, De Cunto G, Lorenzini S, Galeazzi M, Lungarella G. Ajulemic acid exerts potent anti-fibrotic effect during the fibrogenic phase of bleomycin lung. Respir Res. 2016 May 6;17(1):49. doi: 10.1186/s12931-016-0373-0. PubMed PMID: 27153807; PubMed Central PMCID: PMC4859981.