ML198

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Chemical Information

Product name：ML198	Purity：98% min
CAS NO：1380716-06-2	Solubility：
Molecular Formula：C₁₇H₁₄N₄O	Package：Package according to customer requirements
Molecular Weight：290.319	Storage：-20 ℃

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Remarks

ML198 is a novel activator and non-inhibitory chaperone of glucocerebrosidase. ML198 serves as a starting point to develop a novel approach towards small molecule treatment for patients suffering from Gaucher disease.

References

1: Rogers S, Patnaik S, Schoenen F, Zheng W, Choi J, Motabar O, Southall N, Westbroek W, Goldin E, Sidransky E, Leister W, Marugan JJ, Aubé J. Discovery, SAR, and Biological Evaluation of Non-inhibitory Chaperones of Glucocerebrosidase. 2012 Mar 27 [updated 2013 Mar 7]. Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-. Available from http://www.ncbi.nlm.nih.gov/books/NBK143537/ PubMed PMID: 23762943.