Product :
Selinexor KPT-330
Shipping and handling fee USD40, Free delivery is qualified when the total value of your order exceeds USD500.If the item is temporarily out of stock. Please email to order@pharm-intermediates.com,we will inform you when we have it in stock.
Chemical Information
| Product name：Selinexor KPT-330 |
Purity：98% min |
| CAS NO：1393477-72-9 |
Solubility：DMSO : ≥ 48 mg/mL (108.28 mM) |
| Molecular Formula：C17H11F6N7O |
Package：Package according to customer requirements. |
| Molecular Weight：443.306 |
Storage：Store at -20℃ |
Remarks
Selinexor, also known as KPT-330, is an orally bioavailable, potent and selective XPO1/CRM1 Inhibitor. Selinexor is effective in acquired resistance to ibrutinib and synergizes with ibrutinib in chronic lymphocytic leukemia. Selinexor potentiates the antitumor activity of gemcitabine in human pancreatic cancer through inhibition of tumor growth, depletion of the antiapoptotic proteins, and induction of apoptosis. Selinexor has strong activity against primary AML cells while sparing normal stem and progenitor cells.