Product :
Bioymifi DR5 Activator
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Chemical Information
| Product name：Bioymifi DR5 Activator |
Purity：98% min |
| CAS NO：1420071-30-2 |
Solubility：DMSO : 23.5 mg/mL (47.54 mM) |
| Molecular Formula：C22H12BrN3O4S |
Package：Package according to customer requirements |
| Molecular Weight：494.317 |
Storage：Store at -20℃ |
Remarks
Bioymifi is an DR5 activator (Kd = 1.2 µM; IC50 = 2 µM). Bioymifi induces apoptosis via the Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) death receptor DR5 independent of TRAIL. Bioymifi can act as a single agent to induce DR5 clustering and aggregation, leading to apoptosis. Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) activates apoptosis through the death receptors DR4 and DR5.