ML-299

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Chemical Information

Product name：ML-299	Purity：98% min
CAS NO：1426916-00-8	Solubility：
Molecular Formula：C₂₃H₂₆BrFN₄O₂	Package：Package according to customer requirements
Molecular Weight：489.381	Storage：-20℃

Quality control

Remarks

ML-299, also known as VU0463568, is a dual PLD1/2 inhibitor (PLD1 IC50 = 6 nM, PLD2 IC50 = 20 nM).

References

1: Scott SA, O’Reilly MC, Daniels JS, Morrison R, Ptak R, Dawson ES, Tower N,
Engers JL, Engers DW, Oguin T, Thomas P, White L, Brown HA, Lindsley CW.
Development of a Selective, Allosteric PLD1/2 Inhibitor in a Novel Scaffold. 2012
Apr 5 [updated 2013 Mar 14]. Probe Reports from the NIH Molecular Libraries
Program [Internet]. Bethesda (MD): National Center for Biotechnology Information
(US); 2010-. Available from http://www.ncbi.nlm.nih.gov/books/NBK143555/
PubMed PMID: 23762925.