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OTSSP167 1431697-89-0
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Chemical Information
Product name:OTSSP167 Purity:98% min
CAS NO:1431697-89-0 Solubility:10 mM in DMSO
Molecular Formula:C25H28Cl2N4O2 Package:Package according to customer requirements
Molecular Weight:487.421 Storage:Store at -20℃
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OTSSP167, also known as OTS167, is an orally available inhibitor of maternal embryonic leucine zipper kinase (MELK) with potential antineoplastic activity. Upon administration, OTS167 binds to MELK, which prevents both MELK phosphorylation and activation; thus inhibiting the phosphorylation of downstream MELK substrates. This may lead to an inhibition of both cell proliferation and survival in MELK-expressing tumor cells.
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