CC-401 Hydrochloride

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Chemical Information

Product name：CC-401 Hydrochloride	Purity：98% min
CAS NO：1438391-30-0	Solubility：DMSO : 100 mg/mL (235.33)
Molecular Formula：C₂₂H₂₅ClN₆O	Package：Package according to customer requirements
Molecular Weight：424.927	Storage：-20℃

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Remarks

CC-401 hydrochloride is a potent inhibitor of all three forms of JNK with Ki of 25 to 50 nM.

References

[1]. Ma FY, et al. A pathogenic role for c-Jun amino-terminal kinase signaling in renal fibrosis and tubular cell apoptosis. J Am Soc Nephrol. 2007 Feb;18(2):472-84.

[2]. Vasilevskaya IA, et al. Inhibition of JNK Sensitizes Hypoxic Colon Cancer Cells to DNA-Damaging Agents. Clin Cancer Res. 2015 Sep 15;21(18):4143-52.