Product :
CTX-0294885
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Chemical Information
| Product name：CTX-0294885 |
Purity：98% min |
| CAS NO：1439934-41-4 |
Solubility：DMSO : ≥ 41 mg/mL (93.62 mM) |
| Molecular Formula：C22H24ClN7O |
Package：Package according to customer requirements |
| Molecular Weight：437.925 |
Storage：Store at -20℃ |
Remarks
CTX-0294885 is a novel broad-spectrum kinase inhibitor. CTX-0294885 exhibits inhibitory activity against a broad range of kinases in vitro. Use of a quantitative proteomics approach confirmed the selectivity of CTx - 0294885 -bound beads for kinase enrichment. Large-scale CTX- 0294885 -based affinity purification followed by LC-MS/MS led to the identification of 235 protein kinases from MDA-MB-231 cells, including all members of the AKT family that had not been previously detected by other broad-spectrum kinase inhibitors. CTX- 0294885 represents a powerful new reagent for analysis of kinome signaling networks that may facilitate development of targeted therapeutic strategies.