Product :
GJ-103 free acid
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Chemical Information
| Product name：GJ-103 free acid |
Purity：99% min |
| CAS NO：1459687-89-8 |
Solubility： |
| Molecular Formula：C16H14N4O3S |
Package：Package according to customer requirements |
| Molecular Weight：342.372 |
Storage：Store at -20℃ |
Remarks
GJ-103 is an active analog of the read-through compound GJ072. Chemical-induced read through of premature stop codons might be exploited as a potential treatment strategy for genetic disorders caused by nonsense mutations.
References
1: Du L, Jung ME, Damoiseaux R, Completo G, Fike F, Ku JM, Nahas S, Piao C, Hu H,
Gatti RA. A new series of small molecular weight compounds induce read through of
all three types of nonsense mutations in the ATM gene. Mol Ther. 2013
Sep;21(9):1653-60. doi: 10.1038/mt.2013.150. Epub 2013 Jun 18. PubMed PMID:
23774824; PubMed Central PMCID: PMC3776636.