Heptaplatin Eptaplatin

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Chemical Information

Product name：Heptaplatin Eptaplatin	Purity：98% min
CAS NO：146665-77-2	Solubility：Soluble in DMSO
Molecular Formula：C₁₁H₂₀N₂O₆Pt	Package：Package according to customer requirements
Molecular Weight：471.364	Storage：Store at -20℃

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Remarks

Heptaplatin (Sunpla) is a new platinum derivative with anticancer activity against various cancer cell lines, including cisplatin-resistant cancer cell lines. Heptaplatin has been reported to have a response rate of 17% as a single agent, and tolerable toxicity in the treatment of advanced gastric cancer.

Properties:
Appearance & Physical State: White Crystalline Powder
Melting Point: 43-49ºC
Boiling Point: 261.5ºC at 760 mmHg
Flash Point: 114ºC
Vapor Pressure: 0.0115mmHg at 25°C

References

1: Liu W, Chen X, Ye Q, Xu Y, Xie C, Xie M, Chang Q, Lou L. A novel water-soluble heptaplatin analogue with improved antitumor activity and reduced toxicity. Inorg Chem. 2011 Jun 20;50(12):5324-6. doi: 10.1021/ic200436u. Epub 2011 May 20. PubMed PMID: 21598993.

2: Al-Anazi KM, Abou-Tarboush FM, Abdel-Samad MF, Farah MA, Al-Faifi MY, Al-Ahmadi BA. Embryo-feto-toxicity of anticancer drug, heptaplatin in laboratory mice. Pak J Biol Sci. 2010 Sep 15;13(18):896-900. PubMed PMID: 23350163.