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Product :

AHU-377 Sacubitril

AHU-377 Sacubitril 149709-62-6
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Chemical Information
Product name:AHU-377 Sacubitril Purity:98% min
CAS NO:149709-62-6 Solubility:DMSO : ≥ 100 mg/mL (243.02 mM)
Molecular Formula:C24H29NO5 Package:Package according to customer requirements
Molecular Weight:411.491 Storage:Store at -20℃
Quality control
COA
Remarks
Sacubitril, also known as AHU377, is angiotensin receptor neprilysin inhibitor being studied for use in combination with valsartan for heart failure. Sacubitril is a prodrug that is activated to LBQ657 by de-ethylation via esterases. LBQ657 inhibits the enzyme neprilysin, which is responsible for the degradation of atrial and brain natriuretic peptide, two blood pressure lowering peptides that work mainly by reducing blood volume.
Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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