CP-105696

Size	Price	Stock	Quantity
Get Quotation Now Add to Cart Bulk Inquiry

Shipping and handling fee USD40, Free delivery is qualified when the total value of your order exceeds USD500.If the item is temporarily out of stock. Please email to order@pharm-intermediates.com,we will inform you when we have it in stock.

Chemical Information

Product name：CP-105696	Purity：98% min
CAS NO：158081-99-3	Solubility：
Molecular Formula：C₂₈H₂₈O₄	Package：Package according to customer requirements
Molecular Weight：428.520	Storage：Store at -20℃

Quality control

Remarks

CP 105696 is a potent and selective leukotriene B4(LTB4) receptor antagonist. In vitro, CP-105696 inhibited LTB4 (0.3 nM) binding to high-affinity LTB4 receptors on human neutrophils with an IC50 value of 8.42 +/- 0.26 nM. The therapeutic potential of CP-105696, an BLT1 inhibitor, prevents and treats arthritis.

References

[1]. Showell HJ, et al. The in vitro and in vivo pharmacologic activity of the potent and selective leukotriene B4 receptor antagonist CP-105696. J Pharmacol Exp Ther. 1995 Apr;273(1):176-84.

[2]. Weringer EJ, et al. Antagonizing leukotriene B4 receptors delays cardiac allograft rejection in mice. Transplantation. 1999 Mar 27;67(6):808-15.