Rasagiline mesylate

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Chemical Information

Product name：Rasagiline mesylate	Purity：98% min
CAS NO：161735-79-1	Solubility：H2O : 25 mg/mL (93.51 mM)
Molecular Formula：C₁₃H₁₇NO₃S	Package：Package according to customer requirements
Molecular Weight：267.344	Storage： Store at -20℃

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Remarks

Rasagiline Mesylate is a selective irreversible MAO-B inhibitor. It displays anti-Parkinsonian activity, exhibits neuroprotective and antiapoptotic activity against several neurotoxins in cell culture.

Synonyms:

methanesulfonic acid,(1R)-N-prop-2-ynyl-2,3-dihydro-1H-inden-1-amine;

(R)-N-(Prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-amine methanesulfonate;

Properties:

Appearance & Physical State: White powder

Density: 1.05 g/cm3

Boiling Point: 305.5ºC at 760 mmHg

Melting Point: 155-158ºC

Flash Point: 146.8ºC

Vapor Pressure: 0.000816mmHg at 25°C

References

[1]. M B Youdim, et al. Rasagiline [N-propargyl-1R(+)-aminoindan], a selective and potent inhibitor of mitochondrial monoamine oxidase B. Br J Pharmacol. 2001 Jan;132(2):500-6.

[2]. Shawna Tazik, et al. Comparative neuroprotective effects of Rasagiline and aminoindan with selegiline on dexamethasone-induced brain cell apoptosis. Neurotox Res. 2009 Apr;15(3):284-90.