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AR-C69931MX Cangrelor

AR-C69931MX Cangrelor 163706-06-7
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Chemical Information
Product name:AR-C69931MX Cangrelor Purity:98% min
CAS NO:163706-06-7 Solubility:Soluble in DMSO
Molecular Formula:C17H25Cl2F3N5O12P3S2 Package:Package according to customer requirements
Molecular Weight:776.359 Storage:Store at -20℃
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COA
Remarks

Cangrelor is a P2Y12 inhibitor, and was approved in June 2015 as an antiplatelet drug for intravenous application. Cangrelor is a high-affinity, reversible inhibitor of P2Y12 receptors that causes almost complete inhibition of ADP-induced platelet aggregate. It is a modified ATP derivative stable to enzymatic degradation. It does not require metabolic conversion to an active metabolite. This allows cangrelor's immediate effect after infusion, and the therapeutic effects can be maintained with continuous infusion.

Properties:
Density: 2.087g/cm3
Boiling Point: 979.004ºC at 760 mmHg
Flash Point: 545.882ºC
Refractive Index: 1.722
Vapor Pressure: 0mmHg at 25°C

References

1: Judge HM, Buckland RJ, Jakubowski JA, Storey RF. Cangrelor inhibits the binding of the active metabolites of clopidogrel and prasugrel to P2Y(12) receptors in vitro. Platelets. 2015 Aug 13:1-5. [Epub ahead of print] PubMed PMID: 26270719.

2: Keating GM. Cangrelor: A Review in Percutaneous Coronary Intervention. Drugs. 2015 Aug;75(12):1425-34. doi: 10.1007/s40265-015-0445-3. PubMed PMID: 26201463.

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.
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